Cascara sagrada

Made from cascara bark — the American buckthorn whose anthraquinone laxative remained in the pharmacopoeias into living memory, and the classical remedy of the obstinate, portal-bound constipation.

SourceWoody plantTrees & shrubs

The whole picture, in one breath

Think of a bowel bound to the portal system: obstinate, chronic constipation with a sensation of fullness in the portal region, the old books' association with jaundice and the torpid liver, and the remedy of the dried-up, bound constitution. The portal-bound constipation: that is Cascara.

The substance, in plain words

Cascara — the bark of the American buckthorn — was a genuine, official laxative of the pharmacopoeias for over a century, its anthraquinone chemistry working the bowel the same way as its cousins senna and the yellow dock of the library. It is among the last of the botanical purgatives to retire; the proving gave the remedy its portal-constipation portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
cold damp weather; morning; sedentary habits; errors of diet.motion; warmth; the bowel moving at last.

Where it acts (organ affinities)

Bowels (chronic constipation), liver and portal system, rectum, general vitality.

Where the classical picture comes from

The official laxative's century-long career gave the proving its frame — the bound bowel and the congested portal; Cascara became the classical remedy of the habitual, portal-bound constipation, standing at the respectable end of the purge family.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Cascara was a genuine, official laxative of the pharmacopoeias — one of the last botanical purgatives in mainstream use, retired as modern bowel medicine advanced. Its anthraquinone chemistry really works — and really warns: chronic stimulant-laxative use is now managed carefully for dependence and electrolyte loss. The bark's career spans the whole era of the purge, honourably concluded.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
SulphurChronic constipation, heatSulphur's is hot and itchy-skinned; Cascara's is portal-bound and bound.
Nux vomicaIrritable, sedentary constipationNux is fiery and spasmodic; Cascara the habitual portal-bound one.
Collinsonia canadensisPiles with constipationCollinsonia's piles alternate with the bowels; Cascara's the bound portal state.
AluminaConstipation without urgingAlumina's is dry, urging-less with faintness; Cascara's portal-bound with the liver link.
Safety. Chronic constipation needs a proper work-up — fibre, fluids, exercise and review of causes; never rely on laxatives long-term without assessment.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica