Chininum sulphuricum

Made from quinine sulfate — the bark salt that conquered malaria and taught medicine cinchonism, and the classical remedy of the periodic fever with the ringing ear.

SourceMadder familyRubiaceae

The whole picture, in one breath

Think of the bark's own signature in remedy form: periodic fevers returning on schedule, violent ringing and roaring in the ears, the deafness of the quinine, the congested head and the pale, bloated face — the books' great anti-periodic beside China. The ringing-ear periodic fever: that is Chininum sulphuricum.

The substance, in plain words

Quinine sulfate is the bark's own salt — the first specific drug in medical history, isolated from Peruvian bark, which conquered malaria and taught medicine the word 'cinchonism': the ringing ears, the deafness, the headache of its own overdose. The proving gave the remedy the overdose's portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
cold damp weather; night; noise; the paroxysm's hour.rest; quiet; warmth.

Where it acts (organ affinities)

Ears (tinnitus, deafness), fever mechanism, head, general vitality.

Where the classical picture comes from

The bark salt's proving gave the overdose's portrait — ringing ears, periodic fevers, the pale bloated face; Chininum sulphuricum became the classical remedy of the bark's own side-effects, the anti-periodic's mirror.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Quinine's real medicine is one of history's greatest: the conquest of malaria, the founding of chemotherapy — the very idea that a specific chemical cures a specific disease. Cinchonism remains textbook toxicology, and the bark's descendants, the artemisinins, continue the conquest today. The salt's career spans four centuries of real pharmacology.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
China officinalisThe bark pairChina is the debility after the fevers; Chininum sulph the ringing-ear periodicity itself.
CedronClockwork feversCedron's fevers keep perfect time; Chininum sulph's bring the ringing ears.
Salicylicum acidumRinging ears, rheumatismSal-acid's ringing rides with rheumatism; Chininum sulph's with the periodic fever.
Natrum salicylicumEar noises of the Boericke supplementNat-salicyl serves the Meniere-like vertigo of the same chapter.
Safety. Ringing ears on any treatment signals review; any returning fever needs diagnosis — malaria, still present in much of the world, is tested and treated, not timed.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica