Mandragora

Made from the mandrake root — the man-shaped root of legend, the tropane alkaloids of the nightshade family, and the classical remedy of the rheumatic and the ulcerated.

SourceNightshade familySolanaceae

The whole picture, in one breath

Think of the legendary root's real portrait: rheumatic pains with the contraction of the muscles, the ulcerated stomach of the old books, the dryness and the delirium of the family, and the books' great mandrake of the nightshade chapter. The legendary-root remedy: that is Mandragora.

The substance, in plain words

The mandrake is the man-shaped root of Mediterranean legend — the root that shrieked when pulled, the witch's familiar of every old tale. Its chemistry is genuinely the nightshade family's: tropane alkaloids, kin to belladonna's atropine and henbane's scopolamine, real and dangerous. The proving gave the legend its clinical portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
cold damp weather; night; motion; exertion.warmth; rest; quiet.

Where it acts (organ affinities)

Muscles and joints (rheumatic contraction), stomach (ulcerated), mouth and throat, mind.

Where the classical picture comes from

The shrieking root of legend proved a real portrait: rheumatic contraction, the ulcerated stomach, the family's dryness and delirium; Mandragora became the classical remedy of the nightshade chapter's legendary member — the witch's root recorded by the old school.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

The mandrake's tropane alkaloids are genuinely the family's — atropine and scopolamine's kin, the chemistry of belladonna and henbane, real, dangerous and still studied. The plant of every old tale carries the same molecules as the era's greatest drugs; the legends were wrong about the shriek but right about the power. The ulcer it portrayed is now gastroenterology's, and real treatment exists.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
BelladonnaNightshade familyBelladonna is the hot, red, dry throbbing; Mandragora the rheumatic contraction and the ulcer.
Hyoscyamus nigerFamily deliriumHyoscyamus suspects and mutters; Mandragora contracts and ulcerates.
Bryonia albaRheumatic contractionBryonia is dry and still; Mandragora is the family's contraction with the ulcerated stomach.
Arsenicum albumBurning, ulcerated stomachArsenicum is anxious, chilly and sipping; Mandragora is the nightshade family's ulcer.
Safety. Any suspected nightshade poisoning is an emergency; persistent stomach pain or weight loss needs assessment; never touch the raw root.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica