Hydrastis canadensis

Made from goldenseal — the yellow-rooted North American herb whose berberine and hydrastine are real alkaloids, and the classical tonic of torpid membranes.

SourceButtercup familyRanunculaceae

The whole picture, in one breath

Think of membranes that have stopped working: thick, yellow, ropy mucus hanging in strings from nose or throat, a weak stomach that ulcerates and will not heal, a torpid liver, and a general 'won't-come-right' debility in pale, flabby people. Ropy yellow catarrh, torpid ulceration: that is Hydrastis.

The substance, in plain words

Goldenseal is the golden-rooted herb of North American forests, rich in berberine and hydrastine — genuine isoquinoline alkaloids. It was the Eclectic school's great tonic, used for ulcers, catarrhs and debility; its chemistry is active enough that modern medicine respects it and folk overuse depletes the wild plant.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
damp cold weather; suppressed discharges; rich food; night air.rest; warmth; open air in dry weather.

Where it acts (organ affinities)

Mucous membranes (stomach, nose, bowel, vagina), liver, skin (sallow), general vitality.

Where the classical picture comes from

The Eclectic physicians used goldenseal for exactly the states the proving confirmed — ropy catarrh, weak ulceration, torpid digestion. The remedy became the chronic-tonic portrait of the library, applied wherever membranes had gone quiet.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Berberine — goldenseal's golden alkaloid — is one of the best-documented botanical actives: antimicrobial, studied in gut infection, diabetes and cholesterol. Hydrastine was an official astringent-uterotonic of the old pharmacopoeia. Goldenseal is a real alkaloid pharmacy, and its wild overharvesting is a modern conservation concern.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
Kali bichromicumRopy stringy mucusKali-bich's ropes are from the sinus and throat with punched-out ulcers; Hydrastis' ropes come with torpid stomach and debility.
Hydrastis vs PhosphorusStomach ulcerPhosphorus' stomach burns with cold-water craving and bleeding; Hydrastis' is weak, ropy and torpid.
Chelidonium majusLiver, jaundiceChelidonium shoots to the right scapula; Hydrastis is the membrane-tonic of yellow ropes.
Calcarea carbonicaFlabby debilityCalcarea is the sour-sweating, egg-craving child; Hydrastis the ropy-catarrh adult.
Safety. Persistent vomiting, blood in vomit or stool, unexplained weight loss and chronic stomach pain need medical evaluation for ulcers and cancer.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica