Lobelia inflata

Made from Indian tobacco — the American herb whose lobeline mimics nicotine, was studied for smoking cessation, and became the classical asthma-with-nausea remedy.

SourcePlant sourceHerbal kingdom

The whole picture, in one breath

Think of asthma married to nausea: a sensation of oppression at the chest, breathlessness with faintness, cold sweat, nausea rising with every paroxysm, and vomiting that ends the attack — worse in cold air, with a weak stomach behind it all. Asthma with nausea, attack ending in vomit: that is Lobelia.

The substance, in plain words

Lobelia is the American 'Indian tobacco', its lobeline an alkaloid that mimics and then blocks nicotine's actions — studied in the twentieth century as a smoking-cessation drug. In overdose it vomits and sweats; in the proving it gave the chest-and-stomach portrait of the classical books.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
cold air; morning; emotional excitement; eatingwarmth; vomiting

Where it acts (organ affinities)

Lungs and respiration, stomach and vomiting centre, circulation, autonomic nerves.

Where the classical picture comes from

Lobelia's overdose pharmacology — nausea, vomiting, sweat, oppression — is the proving; clinically the remedy attached to the dyspeptic asthmatic whose attacks ended at the basin, a figure well known to the old practitioners.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Lobeline's nicotine-mimicry made it a genuine candidate drug for smoking cessation in the twentieth century — a real pharmacological lead, since abandoned for better agents. Lobelia remains a working example of an autonomic-active plant, its chemistry authentically on the nicotinic pathway.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
IpecacuanhaNausea with chest complaintsIpecac's nausea is constant with clean tongue; Lobelia's is married to the asthma attack.
Arsenicum albumAnxious breathlessnessArsenicum is chilly, midnight-worse and sipping; Lobelia is nauseated and vomiting.
Grindelia robustaAsthma, sleep disorderGrindelia stops breathing on falling asleep; Lobelia vomits at the attack's end.
Antimonium tartaricumRattling, drowsyAnt-tart rattles and sleeps; Lobelia oppresses and vomits.
Safety. Asthma attacks with faintness, blue lips or inability to speak need emergency care; severe breathlessness is never to be managed at home.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica