Rauwolfia serpentina

Made from the snakeroot of the Himalayas — the plant Ayurveda used for the mind and whose reserpine became the first modern tranquilliser and blood-pressure drug.

SourcePlant sourceHerbal kingdom

The whole picture, in one breath

Think of a mind both over-wound and sedated: drowsiness with an irritable, over-sensitive nervous system, periodic madness-like states of the old books, a slow, soft pulse with the sedation, and the strange calm that descends like a curtain. The sedated-curtain remedy: that is Rauwolfia.

The substance, in plain words

The snakeroot is the slender root of a Himalayan shrub, used in Ayurveda for centuries for madness, snakebite and the 'wind' of the body. Its chemistry gave medicine reserpine — the first modern tranquilliser and the first rationally developed blood-pressure drug, the opening of the psychopharmacology era. The proving gave the remedy the sedation portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
cold damp weather; night; emotional excitement.rest; quiet; warmth.

Where it acts (organ affinities)

Mind and nervous system, circulation (pulse), stomach, general vitality.

Where the classical picture comes from

The Ayurvedic snakeroot's proving gave the sedated-curtain portrait; the old books used it for the periodic madness states and the over-wound nervous system — decades before its chemistry opened the era of tranquillisers.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Reserpine is genuinely one of the most consequential molecules of the twentieth century: isolated from Rauwolfia in 1952, it became the first modern antipsychotic and the first effective blood-pressure drug — the opening shot of psychopharmacology, and a landmark in the treatment of hypertension worldwide. The plant Ayurveda used for the mind gave medicine its first tranquilliser: no remedy in this library carries so direct a line from the old pharmacy to the modern one.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
OpiumDrowsy statesOpium is heavy, dark and painless; Rauwolfia is the sedated curtain over the irritable nerve.
Hyoscyamus nigerOver-wound deliriumHyoscyamus suspects and exposes; Rauwolfia sedates the same over-wound system.
Digitalis purpureaSlow pulseDigitalis slows with nausea and dropsy; Rauwolfia slows with the curtain of calm.
Passiflora incarnataThe calmativesPassiflora is the gentle herbal calmative; Rauwolfia is its powerful alkaloid cousin — the cautionary tale of the same family.
Safety. Changes in mood, drowsiness or a slowing pulse on any remedy need review; mental-health symptoms deserve proper care — modern treatment is effective.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica