Bufo rana

Made from the toad's poison — the bufotenin of the sorcerers' texts, a genuine molecule of modern psychopharmacology, and the classical remedy of the convulsive state.

SourceAnimal sourceAnimal kingdom

The whole picture, in one breath

Think of a mind slipping toward seizure: strange sensations before the fit, the convulsion itself with the biting and the fixed stare, the dullness and anger after, and the books' great toad remedy of the convulsive diathesis. The seizure's shadow: that is Bufo.

The substance, in plain words

The common toad carries its poison in the glands of its skin — bufotenin and the bufotoxins, genuinely psychoactive molecules studied in modern psychopharmacology, the chemistry behind the toad's ancient fame in sorcery and its modern notoriety. The proving gave the toad the convulsive portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
night; emotional excitement; the cycle's approach; light.rest; quiet; warmth.

Where it acts (organ affinities)

Nervous system (convulsions, aura), mind, general vitality.

Where the classical picture comes from

The toad's poison proved the convulsive portrait; Bufo became the classical remedy of the epileptiform state — the sorcerers' toad recorded by the old school with the same respect the psychopharmacologists would later give its molecules.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Bufotenin is genuinely psychoactive — a serotonin-family alkaloid of the toad's skin, studied in modern psychopharmacology and the subject of real, serious research into consciousness and seizure. The toad of the sorcerers carries molecules the laboratory respects; the convulsions it portrayed are now neurology's, treated with real, effective anticonvulsants.

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
Cicuta virosaConvulsionsCicuta's is the arching rigid spasm; Bufo's is the aura, the fixed stare and the cycle's link.
Cuprum metallicumSpasms and convulsionsCuprum's cramps end the cough in spasm; Bufo's is the epileptiform fit with the aura.
Hydrocyanicum acidumConvulsive familyHydrocyanic's convulsions alternate; Bufo's come with the aura and the dullness after.
AbsinthiumOver-wound nervesAbsinthium is the trembling sleeplessness; Bufo is the seizure's shadow with the aura.
Safety. Any seizure is a medical emergency on first occurrence; recurrent seizures need neurological care — modern anticonvulsants are effective.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica