Gelsemium sempervirens

Made from yellow jasmine — the climbing trumpet flower of the American South whose gelsemine alkaloids quietly paralyse nerve and eyelid.

SourcePlant sourceHerbal kingdom

The whole picture, in one breath

Think of trembling paralysis before the event: the student unable to stand for the exam, the speaker whose legs shake and knees knock, eyelids drooping, body heavy as lead, mind dull and drowsy, diarrhea from pure anticipation — relief only after it is over. Anticipatory trembling, heaviness, drooping lids: that is Gelsemium.

The substance, in plain words

Yellow jasmine is a woody vine of the southern United States whose flowers and root carry gelsemine and related alkaloids. The poison slowly paralyses — first the eyelids and eye muscles (double vision, ptosis), then the limbs — a creeping motor-sedation that shaped the entire remedy portrait.

The traditional picture Classical sources

The inner state

The body

Modalities (worse and better factors)

Worse from ⬇Better from ⬇
damp weather; before events and excitement; emotion and bad news; heat of the sun.open air; urination; being quiet.

Where it acts (organ affinities)

Motor nerves and muscles, eyes and eyelids, spinal cord, emotional anticipation.

Where the classical picture comes from

Gelsemium poisoning was mapped in the American South: ptosis, diplopia, drooping face, limb weakness and respiratory slowing — the creeping paralysis the provings confirmed. The remedy's emotional keynote grew from watching these same states arrive with stage fright.

The substance in real medicine Pharmacology

What this section is: the pharmacology and toxicology of the source substance. It is not clinical evidence that a homeopathic preparation of it treats any condition. What controlled trials do and do not show is set out on the Evidence page.

Gelsemium alkaloids are studied in modern pharmacology for their interaction with neuronal receptors — a research subject in muscle and nerve signalling — but no therapeutic drug emerged; the plant is simply too dangerous. Its portrait survives in two places: the toxicology textbook, and the phrase 'paralysed by stage fright.'

Look-alikes (how the classical authors told it apart)

RemedyLooks similar because…Tells it apart because…
Argentum nitricumAnticipatory anxietyArg-nit is hurried, impulsive and craves sugar before the event; Gelsemium is heavy, dull and trembling.
Nux vomicaIrritability, digestive upsetNux is fiery, chilly and morning-worse; Gelsemium is drowsy, trembling and anticipation-worse.
CausticumParalysis tendencyCausticum's paralysis creeps slowly with hoarseness and injustice; Gelsemium's comes with drooping lids and trembling.
Aconitum napellusFear, restlessnessAconite is the sudden terror of death; Gelsemium the trembling dread of the performance.
Safety. Drooping eyelids with double vision, difficulty swallowing or breathing are neurological emergencies — seek urgent care.
Compiled by Dr. Sohil Momin, BHMS · Open Materia Medica